GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | trans | rs1056667 | 1 | rs9467779 | chr6:26536687 | ZNF322B | chr9:99957633-99961910:- | -0.54 | -10.29 | 1.48E-22 | Educational attainment |
| THCA | trans | rs1056667 | 1 | rs9467782 | chr6:26542773 | ZNF322B | chr9:99957633-99961910:- | 0.54 | 10.32 | 1.16E-22 | Educational attainment |
| THCA | trans | rs1056667 | 1 | rs9467783 | chr6:26542894 | ZNF322B | chr9:99957633-99961910:- | 0.53 | 9.98 | 2.0E-21 | Educational attainment |
| THCA | trans | rs1056667 | 1 | rs9467787 | chr6:26556769 | ZNF322B | chr9:99957633-99961910:- | 0.57 | 11.17 | 6.52E-26 | Educational attainment |
| THCA | trans | rs1056667 | 1 | rs9467791 | chr6:26562486 | ZNF322B | chr9:99957633-99961910:- | -0.58 | -11.07 | 1.71E-25 | Educational attainment |
| THCA | trans | rs1056667 | 1 | rs9467796 | chr6:26568411 | ZNF322B | chr9:99957633-99961910:- | 0.59 | 11.31 | 1.98E-26 | Educational attainment |
| THCA | trans | rs1056667 | 1 | rs9467797 | chr6:26568473 | ZNF322B | chr9:99957633-99961910:- | 0.59 | 11.31 | 1.98E-26 | Educational attainment |
| THCA | trans | rs965513 | 1 | rs965513 | chr9:100556109 | BMPR1A | chr10:88516396-88684944:+ | -0.24 | -6.3 | 6.58E-10 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs965513 | chr9:100556109 | CLDN2 | chrX:106143394-106174091:+ | 0.26 | 6.02 | 3.46E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs965513 | chr9:100556109 | EML5 | chr14:89081205-89259157:- | 0.3 | 6.88 | 1.9E-11 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs965513 | chr9:100556109 | EPDR1 | chr7:37960163-37991539:+ | 0.32 | 7.17 | 2.86E-12 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs965513 | chr9:100556109 | GGT5 | chr22:24615623-24641110:- | 0.26 | 5.98 | 4.48E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs965513 | chr9:100556109 | LRRC42 | chr1:54412037-54433839:+ | -0.23 | -5.96 | 4.79E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs965513 | chr9:100556109 | NKX6-1 | chr4:85414436-85419387:- | 0.48 | 8.35 | 7.4E-16 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs965513 | chr9:100556109 | PLCE1 | chr10:95753746-96088146:+ | 0.27 | 6.07 | 2.66E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |